Lutetium-177 PSMA Therapy

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    Lutetium-177 PSMA therapy is a method of treatment whereby a radioactive isotope called lutetium-177 (Lu-177) is injected into the body to specifically target prostate cancer cells in patients with metastatic, hormone-refractory prostate cancer.

    Lutetium-177 PSMA therapy is part of a group of therapies that are known as targeted alpha therapy. This type of treatment uses alpha particle emitting radionuclides like Lu-177 to kill and destroy cancer cells while leaving healthy tissues unharmed or minimally affected by radiation.
    What Is It?
    What is Lutetium-177 PSMA Therapy?
    PSMA is a radioactive isotope used in targeted prostate cancer therapy. It targets the prostate specific membrane antigen (PSMA), which is found on the surface of certain cells in the prostate, including cancerous ones. The lutetium-177 PSMA treatment can be injected into your body, where it attaches itself to this antigen and is absorbed by nearby tissues. This process helps destroy cancer cells without harming surrounding healthy tissue.
    Why Lutetium-177 PSMA?
    Here are some reasons why you might want to consider lutetium-177 PSMA therapy:
    • It’s radioactive so it can be used to treat prostate cancer.
    • Lutetium-177 PSMA is also known as 177Lu.
    Who Can Receive This Treatment?
    • You must have prostate cancer that is PSMA-positive.
    • Your tumor must also be classified as low or intermediate grade.
    • Finally, you must have a good performance status (you should feel well enough to perform normal daily activities).
    Lutetium-177 PSMA Therapy is a new treatment option for men with metastatic prostate cancer, and potentially for those with low-risk cancer. It’s recommended that you talk to your doctor about whether Lutetium-177 PSMA Therapy might be right for you.
    Lutetium-177 PSMA is a promising new therapy for the treatment of prostate cancer. This treatment offers a number of advantages over other traditional therapies, including less side effects and improved survival rates. If you have been diagnosed with prostate cancer, your doctor may recommend this treatment as part of your care plan.

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